General health

Depakote

Depakote

Depakote is used to heal seizure disorders, convulsions, to prevent migraine and treat acute manic episodes associated with bipolar disorder.

Depakote 500 mg (Normal Dosage)

Package Price Savings Order
60 pills

10% discount on all future orders

$113 only $1.88 per pill Add to cart
90 pills

10% discount on all future orders

$165 only $1.83 per pill $4.21 Add to cart
120 pills

Free registered mail shipping

10% discount on all future orders

$209 only $1.74 per pill $16.61 Add to cart
180 pills

Free registered mail shipping

10% discount on all future orders

$299 only $1.66 per pill $39.41 Add to cart

Depakote 250 mg (Low Dosage)

Package Price Savings Order
30 pills

10% discount on all future orders

$39.99 only $1.33 per pill Add to cart
60 pills

10% discount on all future orders

$67.99 only $1.13 per pill $11.81 Add to cart
90 pills

10% discount on all future orders

$94.99 only $1.06 per pill $24.71 Add to cart
120 pills

10% discount on all future orders

$120 only $1 per pill $39.61 Add to cart
180 pills

10% discount on all future orders

$176 only $0.98 per pill $63.41 Add to cart
360 pills

Free registered mail shipping

10% discount on all future orders

$338 only $0.94 per pill $141 Add to cart

Depakote 125 mg (Extra Low Dosage)

Package Price Savings Order
30 pills

10% discount on all future orders

$29.99 only $1 per pill Add to cart
60 pills

10% discount on all future orders

$51.99 only $0.87 per pill $8.01 Add to cart
90 pills

10% discount on all future orders

$67.99 only $0.76 per pill $22.01 Add to cart
120 pills

10% discount on all future orders

$85.99 only $0.72 per pill $34.01 Add to cart
180 pills

10% discount on all future orders

$119 only $0.66 per pill $61.01 Add to cart
360 pills

Free registered mail shipping

10% discount on all future orders

$223 only $0.62 per pill $137 Add to cart
Common use

Depakote contains Divalproex sodium, the substance which interacts with certain substances in the brain and increases the concentration of gamma-aminobutyric acid (GABA), which is a neurtransmitter. The drug is used to treat seizure disorders, the manic phase of bipolar disorders, to prevent migraine headaches.


Dosage and direction

The recommended initial dose for treatment of acute mania due to bipolar disorder is 750 mg daily taken in divided doses. For prevention of migraines take 250 mg twice daily. To treat seizures take initial dose calculated as 10-15 mg/kg/day, the dose should be increased gradually by 5-10 mg/kg/day every week to achieve the desired effect. Do not exceed the recommended dose and follow all recommendations of your health care advisor. Drink plenty of water during treatment. Liver function should be controlled on a regular basis to avoid harmful effects. Swallow the pill whole, do not crush or chew it. Inform your doctor immediately if you suppose that the medication does not work properly to prevent seizures. Do not stop taking the medicine without your doctor's permission even if you feel better.


Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.


Overdose

Depakote overdose symptoms include weak pulse, drowsiness, shallow breathing, somnolence, heart block, loss of consciousness, and deep coma. In case of the suspected overdose contact your doctor immediately and seek for immediate medical attention.


Storage

Store at room temperature 15-30 C (59-86 F) away from moisture and heat.


Precautions

Life-threating hepatic failure may develop, this is most likely to occur in children under two years of age especially if they if they have a metabolic disorder or a brain disease causing mental impairment (multiple sclerosis, Huntington disease, Creutzfeldt-Jacob disease, a brain injury or infection). Liver failure symptoms include malaise, lethargy, weakness, facial edema, vomiting, anorexia. Depakote also may cause rare cases of pancreatitis resulting in fatalities, which may suddenly appear even after several years of treatment with Depakote. Dose adjustment is needed in the patients with a bleeding or blood clotting disorder, a history of brain disorder, head injury, or coma, a family history of a urea cycle disorder, a family history of infant deaths with unknown cause, HIV or CMV (cytomegalovirus) infection. Suicide thoughts are also possible during treatment with the drug.


Contraindications

The medication cannot be administered to the patients with hepatic diseases, significant hepatic dysfunction known urea cycle disorders.


Drug interaction

The following drugs may interact with Depakote: topiramate (Topamax), tolbutamide (Orinase), a blood thinner such as warfarin (Coumadin), aspirin or acetaminophen (Tylenol), clozapine (Clozaril, FazaClo), diazepam (Valium), zidovudine (Retrovir), meropenem (Merrem), rifampin (Rifadin, Rimactane, Rifater), ethosuximide (Zarontin), indomethacin (Indocin), nabumetone (Relafen), ibuprofen (Motrin, Advil), naproxen (Naprosyn, Aleve), diclofenac (Voltaren, Cataflam, Arthrotec), ketorolac (Toradol) and aspirin. Such medicines as warfarin or heparin if used concomitantly with Depakote may affect blood clotting and lead to abnormal bleeding. Aspirin and felbamate (Felbatol) reduce catabolism of Depakote and hereby increase its blood concentrations. On the contrary phenytoin (Dilantin), Rifampin (Rifadin; Rimactane), carbamazepine (Tegretol) reduce its blood concentrations. Absorptin of Depakote is reduced by Cholestyramine (Questran), therefore intake of Depakote should be separated by at least two hours before or six hours after doses of cholestyramine.

Depakote can significantly increase concentrations in blood of lamotrigine (Lamictal), zidovudine (AZT), ethosuximide (Zarontin), diazepam (Valium) and phenobarbital, thereby increasing their concentrations in blood.


Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Possible side effect

The most common reported side effects are: nausea, somnolence, dizziness, vomiting, asthenia, abdominal pain, dyspepsia, rash, diarrhea, weight loss, tremors, low fever, dark urine, clay-colored stools. In some cases alopecia (loss of hair), itching and sensitivity to sunlight occur. More rare but serious adverse reactions include pancreatitis, liver injury, and abnormal bleeding. Liver is more likely to occur in children. The risk increases when a patient is taking two more more anti-seizure drugs. Symptoms of damaged liver are malaise, weakness, jaundice, swelling in the face, vomiting, loss of appetite.


Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents
Country Shipping method Delivery time Price  
Delivery 14 - 21 days 10$ Tracking# available in 4 days
Delivery 5 - 9 days 30$ Tracking# available in 2 days
Shipping worldwide Confidentiality and anonymity guarantee
Safe and secure Discreet looking packages
Dispatch orders within 24 hours 100% success delivery

Customers who viewed this item also viewed

Customers also bought